Reds vs. Nationals prediction, odds, line, begin time: 2025 MLB picks, finest bets for July 23 by confirmed mannequin

The Washington Nationals host the Cincinnati Reds at Nationals Park on Wednesday within the closing sport of their midweek sequence. The Nationals received the primary two video games of the sequence, together with a 6-1 win behind a house run from Josh Bell on Tuesday. Washington is 41-60 general and 21-30 at residence, whereas the Cincinnati is 52-50 general are 24-28 on the street this season. Nick Lodolo (7-6, 3.33 ERA) is the projected beginning pitcher for the Reds, whereas Michael Soroka (3-7, 5.10 ERA) is scheduled to begin for the Nationals.

First pitch from Nationals Park in Washington D.C. is about for 12:05 p.m. ET. Cincinnati is a -140 favourite on the cash line (threat $140 to win $100) within the commander-in-chief Nationals vs. Reds odds from DraftKings Sportsbook, whereas the overall variety of runs Vegas thinks shall be scored, or the over/beneath, is 9. Earlier than making any Reds vs. Nationals picks, you’ll want to see the MLB predictions and betting advice from SportsLine’s proven computer simulation model.

The SportsLine Projection Mannequin simulates each MLB sport 10,000 occasions. It entered Week 17 of the 2025 MLB season 46-43 on top-rated MLB picks. It has excelled making residence run prop picks this season, returning greater than 40 items of revenue. Anyone following at sportsbooks and on betting apps might have seen robust returns.    

Now, the mannequin has set its sights on Reds vs. Nationals and simply locked in its picks and MLB predictions. You can head to SportsLine now to see the model’s picks. Listed here are a number of MLB odds and betting strains for Nationals vs. Reds, which you may get in on with a DraftKings promo code or a FanDuel promo code.

Why the Reds can win

The Reds are within the thick of the Nationwide League playoff race. Cincinnati shall be motivated to snap its three-game dropping streak within the closing matchup of this mid-week sequence. The Reds enter Wednesday’s sport with the sixth-best run differential mark within the Nationwide League (+35). 

Cincinnati is paced by one of many premier younger gamers in MLB in shortstop Elly De La Cruz. The 23-year-old is a two-time MLB All-Star choice, and probably the most bodily gifted gamers within the sport. De La Cruz enters Wednesday batting .279 with 18 residence runs, 65 RBI, and 26 stolen bases. See which team to back at SportsLine.

Why the Nationals can win

The Nationals are in final place within the Nationwide League East, however have performed properly as of late, profitable three of 5 video games since getting back from the All-Star break. Washington received every of the primary two video games on this sequence, and have been dominant on the mound on Tuesday, with 5 pitchers combining to restrict the Reds to at least one run. 

Offensively, the Nationals are paced by left fielder James Wood and shortstop CJ Abrams. Wooden enters Wednesday batting .272 with 24 residence runs, 70 RBI, and 14 stolen bases. Abrams is batting .279 with 13 residence runs, 37 RBI, and 20 stolen bases. See which team to back at SportsLine. 

Find out how to make Nationals vs. Reds picks

SportsLine’s mannequin is leaning Over on the overall, projecting 9.5 mixed runs, and it says one aspect of the cash line hits in over 60% of laptop simulations. You can head to SportsLine to see the model’s MLB picks. 

So who wins Reds vs. Nationals, and which aspect of the cash line hits over 60% of the time? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and discover out.